Document Type

Article

Disciplines

Medicine and Health Sciences | Physical Sciences and Mathematics

Abstract

Glutathione-decorated 5 nm gold nanoparticles (AuNPs) and oppositely charged poly(allylamine hydrochloride) (PAH) were assembled into {PAH/AuNP}n films fabricated layer-by-layer (LbL) on pyrolytic graphite (PG) electrodes. These AuNP/polyion films utilized the AuNPs as electron hopping relays to achieve direct electron transfer between underlying electrodes and redox proteins on the outer film surface across unprecedented distances >100 nm for the first time. As film thickness increased, voltammetric peak currents for surface myoglobin (Mb) on these films decreased but the electron transfer rate was relatively constant, consistent with a AuNP-mediated electron hopping mechanism.

Comments

Electroanalysis. Author manuscript; available in PMC 2013 May 29. Published in final edited form as: Electroanalysis. 2012 May 1; 24(5): 1129–1140. Published online 2012 April 20. doi: 10.1002/elan.201200079 PMCID: PMC3666353 NIHMSID: NIHMS463119

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