Date of Completion

Spring 4-26-2024

Thesis Advisor(s)

Catherine J. Andersen

Honors Major

Nutritional Sciences

Disciplines

Dietetics and Clinical Nutrition | Endocrine System Diseases | Immune System Diseases | Medicine and Health Sciences | Nutritional and Metabolic Diseases

Abstract

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting approximately 5-15% of women of reproductive age. Characterized by symptoms such as hyperandrogenism, ovulatory dysfunction, and insulin resistance, PCOS is also linked with significant health complications including metabolic syndrome, cardiovascular diseases, and type 2 diabetes. Recent studies highlight the critical role of immune dysfunction and chronic inflammation in exacerbating PCOS pathology, suggesting that managing these immune responses could alleviate the broader health impacts of the disorder.

Nutritional interventions, particularly those targeting immune and inflammatory pathways, have emerged as promising strategies for managing PCOS. Among various dietary components, the intake of whole eggs appears beneficial due to their rich content of essential fatty acids, high-quality protein, and micronutrients like vitamin D and selenium, which are known to modulate immune function and inflammation. Research indicates that eggs can influence lipid profiles and inflammatory markers, thereby potentially mitigating some of the metabolic and reproductive complications associated with PCOS.

This scientific literature review discusses the interplay between inflammation, immune activity, and PCOS, focusing on how dietary intake of eggs could influence these interactions. While current studies provide foundational insights, there is a need for further research to unravel the mechanisms by which eggs could affect PCOS-specific health outcomes. Such investigations are crucial for developing targeted nutritional guidelines that could form part of a holistic strategy for managing PCOS, reducing its health burden, and improving the quality of life for affected women.

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