Date of Completion
7-20-2012
Embargo Period
7-20-2012
Advisors
Michael B. Smith, Amy Howell
Field of Study
Chemistry
Degree
Master of Science
Open Access
Open Access
Abstract
This thesis aims at the evaluation of the best amide bonding strategy that places a fluorescence aminomethyl coumarin tag onto a LMW organic acid in aqueous solution. A three-stage study was conducted. First, a suitable aminomethyl coumarin fluorophore was synthesized. Second, a library of acid-derivatized standards was synthesized for use in optimizing the anticipated HPLC separation of a mixture of LMW acids expected to be found in marine samples. Third, the aforementioned amide coupling strategies were screened to identify the most applicable method for our reaction conditions to the tagging of LMW organic acids in a large number of field samples.
Recommended Citation
Gismervik, Brian C., "Fluorescence Tagging of Marine Low Molecular Weight Carboxylic Acids" (2012). Master's Theses. 316.
https://digitalcommons.lib.uconn.edu/gs_theses/316
Major Advisor
Christian Brueckner