Date of Completion
5-8-2015
Embargo Period
4-23-2015
Keywords
Organofluorine; Continuous Flow Processing; Organic Chemistry; Oxoammonium Salts; Oxidation; Synthetic Methods; Oxidative Functionalization; Computational Chemistry; Organosilicon; Carbocations
Major Advisor
Dr. Nicholas E. Leadbeater
Associate Advisor
Dr. William F. Bailey
Associate Advisor
Dr. James M. Bobbitt
Associate Advisor
Dr. Mark W. Peczuh
Associate Advisor
Dr. Edward J. Neth
Field of Study
Chemistry
Degree
Doctor of Philosophy
Open Access
Campus Access
Abstract
The development of new synthetic methodologies is critical to the advancement of organic chemistry. Development of such methods enables future chemist to chart new chemical territory and do so with precision. Three areas for methods development have been successfully explored: access to fluorinated motifs (perfluoroalkyl ketones & cyclopropanes), oxoammonium salt-based oxidative reactions (experimentally and computationally), and continuous-flow chemistry. These areas not only garner significant attention in the current literature but represent a central theme to this work: performing synthetically useful chemical transformations in a more efficient (and possibly more environmentally friendly) manner.
Recommended Citation
Kelly, Christopher B., "Advances in Organofluorine Chemistry, Novel Oxoammonium-Cation Mediated Transformations, and the Utilization of Emerging Technologies for Organic Reactions" (2015). Doctoral Dissertations. 713.
https://digitalcommons.lib.uconn.edu/dissertations/713