Document Type



Medicine and Health Sciences | Oral Biology and Oral Pathology


Oral mucositis refers to erythematous and ulcerative lesions of the oral mucosa observed in patients with cancer being treated with chemotherapy, and/or with radiation therapy to fields involving the oral cavity. Lesions of oral mucositis are often very painful and compromise nutrition and oral hygiene as well as increase risk for local and systemic infection. Mucositis can also involve other areas of the alimentary tract; for example, gastrointestinal (GI) mucositis can manifest as diarrhea. Thus, mucositis is a highly significant and sometimes dose-limiting complication of cancer therapy.



Dent Clin North Am. Author manuscript; available in PMC 2009 January 1. Published in final edited form as: Dent Clin North Am. 2008 January; 52(1): 61–viii. doi: 10.1016/j.cden.2007.10.002 PMCID: PMC2266835 NIHMSID: NIHMS38513