Medicine and Health Sciences
The appropriate treatment for clinically localized prostate cancer continues to generate controversy. For men with low grade disease it is unclear whether surgery or radiati on therapy provides a survival advantage over active surveillance, and among men with high grade disease it is unclear how many derive a substantial beneﬁt from either intervention. No trial has yet to compare surgery and radiation with observation, but the recent update of the Scandinavian Prostate Cancer Group 4 study suggests that radical prostatectomy provides a signiﬁcant survival advantage for younger men with intermediate grade diseas
Albertsen, Peter C., "Does a Positive Margin Always Mandate Adjuvant Radiotherapy?" (2015). UCHC Articles - Research. 288.