Document Type



Medicine and Health Sciences


Currently available diagnostic techniques can be unreliable in the diagnosis of
delayed fracture healing in certain clinical situations, which can lead to increased complication rates and costs to the health care system. This study sought to determine the utility of positron emission tomography (PET) scanning with 18F-fluoride ion, which localizes in regions of high osteoblastic activity, and 18F-fluorodeoxyglucose (FDG), an indicator of cellular glucose metabolism, in assessing bone healing in a rat femur fracture model.


Published in final edited form as:
Eur J Nucl Med Mol Imaging. 2007 August ; 34(8): 1291–1301. doi:10.1007/s00259-006-0280-6.