Document Type



Life Sciences | Medicine and Health Sciences


The Virtual Cell (VCell) is a unique computational environment for modeling and simulation of cell biology. It has been specifically designed to be a tool for a wide range of scientists, from experimental cell biologists to theoretical biophysicists. The models created with VCell can range from the simple, to evaluate hypotheses or to interpret experimental data, to complex multi-layered models used to probe the predicted behavior of spatially resolved, highly non-linear systems. In this Chapter, we discuss modeling capabilities of VCell and demonstrate representative examples of the models published by the Virtual Cell users.


Int Rev Cell Mol Biol. Author manuscript; available in PMC 2012 December 11. Published in final edited form as: Int Rev Cell Mol Biol. 2010; 283: 1–56. doi: 10.1016/S1937-6448(10)83001-1 PMCID: PMC3519358 NIHMSID: NIHMS423262