Date of Completion
simulation, curvature, membranes, mitochondria
Field of Study
Molecular and Cell Biology
Doctor of Philosophy
Biomembranes are essential to cell structure and function. The function of these membranes is dependent not just on their composition of lipids and proteins, but also the distinct morphologies and shapes they present. In recent years, both experiments and simulations have begun to explore the relationship between membrane function and shape, but in this field, there is much to still be explored. The bulk of this work is dedicated to the development and application of techniques to build and study curved membranes in molecular dynamics simulations, using mitochondrial membranes as the primary biological system of study.
Boyd, Kevin, "A Novel Approach to Generating Lipid Membranes of Arbitrary Shape and Composition" (2019). Doctoral Dissertations. 2235.